Association of <b>IL-6</b> C-572G Gene Polymorphism with Anti-E Production

the study of aaag repeat polymorphism in promoter of errg gene and its association with the risk of breast cancer in isfahan region

چکیده: سرطان پستان دومین عامل مرگ مرتبط با سرطان در خانم ها است. از آنجا که سرطان پستان یک تومور وابسته به هورمون است، می تواند توسط وضعیت هورمون های استروئیدی شامل استروژن و پروژسترون تنظیم شود. استروژن نقش مهمی در توسعه و پیشرفت سرطان پستان ایفا می کند و تاثیر خود را روی بیان ژن های هدف از طریق گیرنده های استروژن اعمال می کند. اما گروه دیگری از گیرنده های هسته ای به نام گیرنده های مرتبط به ا...

Association of interleukin-6 -572G/C polymorphism with intracranial aneurysms risk: a meta-analysis

Intracranial aneurysm is mainly caused by the weakening of the arterial wall. The aim of the present article was to determine whether the interleukin-6 (IL-6) gene -572G/C polymorphism is correlated with intracranial aneurysms. The PubMed and Embase databases were retrieved to identify eligible IL-6 gene -572G/C polymorphism studies that examined the susceptibility to intracranial aneurysms ris...

Association of IL-19 Gene Polymorphism (rs2243191T / C) with occurrence of preeclampsia in pregnant women

Introduction: Preeclampsia, the most common, yet unknown, pregnancy-related disease, is the leading cause of maternal mortality worldwide. Increased systemic inflammatory factors as a result of decreased serum levels of anti-inflammatory cytokines during pregnancy have made inflammation a key role in preeclampsia. In the present study, the relationship between the interleukin 19 polymorphism as...

Association of Apolipoprotein E Polymorphism with Susceptibility to Multiple Sclerosis

Interleukin-6 -572G/C polymorphism and prostate cancer susceptibility.

Strong evidence suggests that cancer-associated inflammation promotes tumor growth and progression, and interleukin-6 (IL6) is an important modulator of inflammation. However, the roles of IL6 and mutations of its corresponding gene in prostate cancer have not been clearly documented. We retrieved data from the Oncomine database concerning IL6 expression in prostate cancer and its role in prost...